Share Request full-text On the performance of Immobilized cells bioreactors utilizing a magnetic field: A review

01.Jan.2017

​This review focuses on the performance of immobilized cells bioreactors utilizing a magnetic field. These reactors utilized immobilized cells on the magnetic particles or beads as the solid phase. All published researches dealing with the performance of Immobilized cells bioreactors utilizing a magnetic from the early sixties of the last century to the present time were considered and analyzed. It was noted that many microorganism such as Saccharomyces cerevisiae were immobilized on different supports in these reactors. These papers used the magnetic field for several purposes mostly for stabilization of the magnetic particles to prevent their washout from the column while operating with relatively high substrate flow rates to enhance mass transfer processes. It was observed that most publications used an axial magnetic field. In addition, most of the magnetic particles were prepared by entrapment. Some comments were presented at the end of the review which shows the gaps in this promising application.