01.Feb.2017
The main objective of this article is devoted to reviewing all previous contributions concerning immobilized enzyme bioreactors utilizing a magnetic field. These reactors used magnetic supports or beads with immobilized enzymes as the solid phase. All published researches from the early beginning after the middle of the last century to the present time are discussed and analyzed. These papers used the magnetic field for several purposes including mixing, attracting the particles to prevent their washout from the column and to operate with higher substrate velocities to enhance mass transfer processes. It was found that axial magnetic field is the most preferable for most researchers. In addition, most of the magnetic particles were prepared by entrapment. Many enzymes such as Glucose oxidase, Urase and Hydrolase were immobilized on different supports in these reactors. In most applications, the magnetic field indirectly enhances the immobilized enzymatic activity and the conversion rate. This enhancement is attributed to the improved mass transfer process between the liquid medium and the immobilized enzyme since the applied magnetic field enables an intensive mixing or the operation with higher medium flow rates. Some comments were presented at the end of the review which shows the gaps in this promising application. https://www.researchgate.net/publication/313416088_Immobilized_enzymes_bioreactors_utilizing_a_magnetic_field_A_review
The main objective of this article is devoted to reviewing all previous contributions concerning immobilized enzyme bioreactors utilizing a magnetic field. These reactors used magnetic supports or beads with immobilized enzymes as the solid phase. All published researches from the early beginning after the middle of the last century to the present time are discussed and analyzed. These papers used the magnetic field for several purposes including mixing, attracting the particles to prevent their washout from the column and to operate with higher substrate velocities to enhance mass transfer processes. It was found that axial magnetic field is the most preferable for most researchers. In addition, most of the magnetic particles were prepared by entrapment. Many enzymes such as Glucose oxidase, Urase and Hydrolase were immobilized on different supports in these reactors. In most applications, the magnetic field indirectly enhances the immobilized enzymatic activity and the conversion rate. This enhancement is attributed to the improved mass transfer process between the liquid medium and the immobilized enzyme since the applied magnetic field enables an intensive mixing or the operation with higher medium flow rates. Some comments were presented at the end of the review which shows the gaps in this promising application.
https://www.researchgate.net/publication/313416088_Immobilized_enzymes_bioreactors_utilizing_a_magnetic_field_A_review
أنا طالبة في الهندسة الصناعية, اختياري لهذا التخصص كان بناءً على أهميته الكبيرة كمهنة في الحاضر والمستقبل ... رغد بركات
الهندسة الصناعية تساعدك على اتخاذ قرارات أفضل، وتعطي أشكالا أخرى من مبادئ الهندسة بشكل عملي وعلمي في آن. ... محمود صلاح
قسم الهندسة الكيميائية قسم جميل جدا تعلمت فيه الكثير ومما تعلمته فيه جدية العمل وروح الفريق الواحد .. ... رغد الشويكي